Fusarium wilt and root-knot nematodes combine to cause a destructive disease of cucurbits in the Varamin area of Iran. Melon varieties (Garmsar and Sooski) at 2-3 leaf stage were inoculated with different populations of root-knot nematode Meloidogyne javanica(2000, 3000, 4000 and 5000 eggs in one kg of autoclaved soil) and then 2 weeks later inoculated with 2×105 microconidia per ml of the fungus agent of Fusarium wilt. Quantitative changes in phenolic compounds were studied 10, 20 and 30 days after inoculation of the fungus. Ten days after inoculation of the fungus in different treatments phenolic compounds as compared with control was increased, but only in Garmsar variety did the fungus + nematode (5000 eggs) treatment show a significant difference against control at %5 level (p<=0.05). Twenty and thirty days after fungus inoculation in either variety, the fungus + nematode treatment with 5000 eggs showed a significant difference at %5 level as compared with control.
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