Water deficit is the prime limiting factor in soybean production in semi-arid regions. Therefore, increasing soybean seed yield requires the selection of resistant and adapted cultivars to dry or water deficit conditions of Iran. In this investigation, in order to study correlation and path coefficients on various traits in soybean, two separate experiments were performed in a 5x5 lattice design in stress and non-stress conditions. Following analysis of variance, which was based on lattice design, the relative efficiency of lattice design was estimated to be less than that of randomized complete block design. Therefore, data statistical analysis was performed in randomized complete block design. Based on the results of indices correlation, HARM, STI, MP & MP were determined as the most suitable drought resistance indices. Based on the results of principle component, two first components totally explained 93.72% of variation among data. The first and second components were named drought tolerance and stress susceptible respectively. Based on the results of drought resistance indices assessment and biplot analysis, Williams was determined to be the most resistant cultivars while Delsoy42io, LD3, A3237, L11 and Linford were the cultivars that exhibited potential seed yield in both environments.